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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e29a9f18010b21233d9505a5cca9df182b44cb4985f0caa698a4bef6d42313d4' 
  AND token = 'X5+EQ5GIa5vUP0rIjq5bStaqK46a6MYySZeECPBZtj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}