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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16f3c1b200190c594706c4eb39da66a01c56273815821fecd171bd7bc8d3eb42' 
  AND token = 'KmyzVJXGnwO1YCg87HzTOi04pHFb2Cc87kCfdil/df0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}