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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23df9a80b17383e125e496642aacddbcc7e2d387e58181ad2c1ad644a29898d6' 
  AND token = 'Qt3RiO6JL3B7O//6qfeCP6b/ODZ/MKMAZsUi9Vst3ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}