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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c55585b6179bc71e8fc708167745318c3a07bce31d3b2d7c0c252a72804db287' 
  AND token = 'JTAxL5xsv6bA36rNfsFWL7gr9k5oTnRSHQDXwibCV5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}