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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b45ce6fb7b7a12f7c5b32cc7921924f9742b4cca3618342eb2273b22c9a84172' 
  AND token = 'SdjVyNpRI8USXj/58PbIAQ/0MxLBMJkVdXaCpC1555Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}