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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54c2e6acbc725af4e87b0441bfc012467cc0975dbe98effdd55c44255eca6d07' 
  AND token = 'UmN4t59tepthBoRwPJgxcTYFVnIqVmDO7uG9C7qoxY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}