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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31e0a43da6f5fb14fb9dafa351fce2739f8566bd0a4e94a494ce54a0c3956332' 
  AND token = 'jDnL+NK3muQmFS1QUneN18KjLC42w0217hTqzsV3Jig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}