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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5649db75958bdb3add18ef9313419f8d35e13bcfd69aacc56f49a15461c5ab19' 
  AND token = '6u4cmvMzcsA+C5Te7UNyiKy++sZY8YYga+NIUASy5PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}