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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08fed460ee1f8f436a60f3de853ad49c48a06ac41f69aaa00963d0e404389f73' 
  AND token = 'D+LtAU/Oub7D4+Hg7ukaySpEUqY3DKFo2kYmL1ee34E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}