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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ec80c2c43a6b9ee20524852e1fe75440b785ac246ff4c157bb57bc1b35f3598' 
  AND token = 'EAp/5GOmLdIobiteaYhBcMUYtWeC1MWb4QwgjzOUb4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}