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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6756078f1020b020d3cac3d2b78e09dc7d85ef6f9181c2d971c68de66e76326' 
  AND token = 'RDFs+xw5qGZqcC65wtsFWwg+55gOkrE68NRITpx/Ju0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}