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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753b2b7e2a388d0f92f097592e1ed3fc022b8b8335529c081d22811d842e3eba' 
  AND token = 'PiAd0ZrQGABI+hwu0HmC9fA76eBnAOwcgSL08YSCGJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}