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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9271c2380083eda5a4983bb2cffe6c4a33c6d2d0a71e717f88981aa9af3491d' 
  AND token = 'SK2i8LR0LH4E+t2/RxqQ/Gawq/olfNJawqNrE+QuxSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}