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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c3ff22e26a7483aad5dc4db177b52631012399391b5e3fe407ef9c4bb345e4' 
  AND token = 'O9L5PKCQgOqnt1xlbl6DG99AOuRDkZ5E3nJGj+fMYKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}