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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f37936a2d390d436ced3f2e07ac282ea34d92e05ad74a21d7a1024a81794622b' 
  AND token = 'u3AOEgoCYpKmGPXl3vOZBrcG38/mc35eCBYwgifKykA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}