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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d4d3bcd9c17f18aa296b1dbcda70846df246012fc94d6065cceef991cc9c08f' 
  AND token = 'uvj/bTvk6L7EU601+VtXtCM0U6VhxDE/+oyGjy87fK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}