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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '554de0b007699392b684fee84c2a97faf761df0d85f3e676ae2fad280a1a0522' 
  AND token = 'Sma9tdNh3KM1x8/8eFt0wfJR/HqKNdkXH+lVP+yIQJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}