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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8a0e7a884a7ced6403149bf4739202bc30dcc62300fc51e1b5f95d79554612f' 
  AND token = 'byK1KMkPB9p5i60e15v57UJ0pZyQbrGbeApCv+BjJts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}