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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38be8f97e12704b437bf2468796067d9281f48fb5e9938057dbc5275b01a1bd' 
  AND token = 'mzrg3kmqcvtZacpkAbe8mfZxz/LvGCMJCpvrbn8nWAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}