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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '979a58efd697082c2c5ea90b0c7644085b4f75f4bb4376ad77f131142c0b4dd8' 
  AND token = 'jAA4lWUjqgTwyzm+C7Z3aMRxMhE5DgXgmMZrpIRrXdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}