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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6283154574c0c3d4e071914d6fc1be7aa4d4e001d6d3a7632e1d85a08e6dc2' 
  AND token = 'DZeVmalFasRDIVE5LpHjq7H3vpfOFONKK22db+cwGKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}