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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '864b7ba558a1cee2bdbd6604649e93db5cc39eeb16c8880abb91bc7720e18166' 
  AND token = 'HRaegzX3Bh5qlxT4VZkgAbn5NFg7DsVWS5XceOzubXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}