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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8af1dc3a9a6ec7b23b559cabf38686d189634f9a5eedc35ec8ff368791516c07' 
  AND token = 'uUN8/KRFW+zOqdGDOdOJ8tozWTCC/rpeCvLmlmr8tVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}