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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d18f323c8c8d7792c0d4a8b7ad76c05872df4ac8163c4884968f5efcbd59a1c' 
  AND token = 'ugOPSdwyd5IGLp+ykibM+nujmy6VvTAcVyesg1nMbsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}