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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28ecc3d84fcb3ad35e9b2f4cc1d526ab2101228dcdab2a7211a5164876e8860e' 
  AND token = 'uClv40IXkFNUGFEl8Ciw0DVIsTKAur4yiR0ZlKJRHQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}