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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f458dcd755ac57770fcf567f8720962b504eb2202b78eac7eec5b83b54b8a5ae' 
  AND token = 'pXZkJ+0ekFUnGwIAseEXVoCL4F6e5YWkKm+OBqLl5g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}