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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e91a51f9be47bd4ada86faa58ea8249c2e62c5435a0ee0c144254987a7807b' 
  AND token = 'UEJCQ1XVb2CVvYdfxlHEJcb9zYKc06X3G5IY6GeOrn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}