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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0880d3f9d48dad0914a931b7208d26792254070c3f78bc9f696deb853d9a71c' 
  AND token = 'ILme28sjUZ2qcEiVSuQSvkXdZPZ2cO+ncDA6u5oQ+zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}