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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f5a9285a88420ef8f0a470ff2d6538f728f506efe542d8a38fbca36ecb1f0b3' 
  AND token = '5we74uMAxsJGRbx4/chNgTex6XXgSV7AM/IUv60TxmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}