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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1186e8a6c4afa23c88d512500b6198de7002c74b5ec7985925624800d318d0ef' 
  AND token = 'zuE9xVlvIRQYrkw9gHbY/fNi6bHGQsZedsSi9n8vjs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}