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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b9afb5a0e83b99195a87b2c59e84ea97a75bc6b1ef01bb89122bf29af4df55' 
  AND token = 'mYMhbxSEfoX/QtoI9aDUG7ysMCpsjiDEsEpwVq+eWW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}