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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8630889baf4fce24102c3f4ca0204e0d437d8f4c5c4dd700229775445bb1201' 
  AND token = 'QeACVt0/cKf2Xj/Q2E8Zr3h6yiCg9KVSmWsf9+xhWRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}