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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec2b25947eda874769ed6a9730ce92bc126fc630af5bfc97b37f395732a254a6' 
  AND token = 'fp4cMJTcp0j9w9cF5Uep8+ug1UVMU+YK6PzhEtboXdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}