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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a96adc304a57cd27a28256f74a18f0aa41e490e0a610a770ab150fae8c59e26a' 
  AND token = 'JtQ9jip3x5Z6eiTa5PV1SZXAdpMAs3uEBRwY5kdSfIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}