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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afbd546cf824f5bf0419b50a154ac2e9269cb01dda6aceb96492a3adfaccdd9a' 
  AND token = 'uXo8cQiY0++GNWX9VBBowuoEAX3dNxuQ4lO+Rg71O/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}