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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ee8e0f70b78d286e897a4ba745cf38d4e1a839b8727b863c5d762f3c2c161eb' 
  AND token = 'IcZKnbNOn/v2SSOJsTOb3Lzy2nzVXJs1ycQAitSbb1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}