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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7208fc9a48e1be0619cce18e3fc78d7420b0dffb4be4d47f183abd56c22d86e4' 
  AND token = 'YlmrKuNRU8LAAHwMazVjd4PcfI4auwIyCQF67j6Uv/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}