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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b25cd98991b0144266023ae76f7ed10d7abbab2f38ad1b904782ed0a176eccd' 
  AND token = 'ODmMgiSRz9rQq7rB2FqGkwTT2OAIw/Zd9mRQxkfKpzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}