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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e0d030a8d9ecd85af7392bb0cb4de289727bc78885e9362d18e8e350cf89fc' 
  AND token = '9qfgY5YAQDkxlU1iDHpLp1PB1gHIXtWlUtY8ieOHywI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}