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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7ec68653431f45e33a9b6ba3b714320661679c32fdbc5cb83f7e8d9608c2006' 
  AND token = '75KXQeb6aeWU1moJjKWyDABopZTz3Gcu0rpbSD4QNNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}