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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ccf02849ef4283a0f4ecafafe309b73bf9078cbc7a484bde26fb7376fc371e8' 
  AND token = 'Xtnc/B9mkbhNOPAX9SUklJeiYtRbYRzuFnBywybOUA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}