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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af16203721926f3c73d6eeb21362fa4cc1c51c556bc2d9df50f16376fbadcb2e' 
  AND token = '/xF39JMe6jTmCsTr/k1PsTiFfgiUNZTuKUfyzmxH4po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}