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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfc5ed9ddce70387c58bcd506c94223e103b5606e4be6fef6fc16a270be03c57' 
  AND token = 'TxUeOZrPQb/vEsP37C16jqIX661RZC00pPY777aDRKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}