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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4bdd37881b93a1bf99bb227fb076f0c08a82fd50bb1f3845be745c174794ff' 
  AND token = 'WlM2GhCcDRnZhoZ02/3rHwoSOWlW3rmiZ8tWhMQ7lpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}