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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ffb45a0ea945e122c70dbcb50100ca2e05c12d886773dd29d2ee7a055b6adc' 
  AND token = 'a2G+0uDWXEncozSQkv2lKa80fWF2uZXTBPjE1qm1HRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}