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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe6506dbf15348c3b1661d778b7b4b74d1ebf7cde2370eb0b019798890b69e36' 
  AND token = '2F3HIQvgOX3uEXF3us8Tcq1nT9oYqIpbmJRJHmI48WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}