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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c62cbb170f32f298d71a2dfd23af7c2783ed8c21dbbb9b8fc78a9adf0824651' 
  AND token = 'EaebDMowTo3/z4sQIT2IvZtYN+pjdtr+0GjwOb82BHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}