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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8de7691f55839c3464d9c4d3a11524a7e9bbdf9c27295ccbbc222c63522f6e8' 
  AND token = 'E4aXdGGvLCliDWqMe8wOBsopGyTdm6jN9Tq9y+xE//E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}