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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd009a6e7ec1bceceaccfe49f41ed87ef0c10bdf2107632ab566ea675c9446cc' 
  AND token = 'v+LqSM6NrdiZW0QxBQfKkUe5xmyND7Csqyl0YYSDPLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}