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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e3c8a3f1a81828b6b9eee495764134d46883259bed00242f8f5205bd225949' 
  AND token = 'Q23+VoRiWQ5QqD1FYSXkDmOV9MrNmH9FkuSDnc/vgH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}